Pyrrolidine, with the chemical formula C4H8N2, is an organic compound classified as a heterocyclic compound.

Properties:

1. Pyrrolidine is a colorless to slightly yellow liquid with a melting point typically ranging from 19 to 21 degrees Celsius and a boiling point of 125-126 degrees Celsius.
2. It undergoes slow oxidation in the presence of air at room temperature.
3. Pyrrolidine exhibits good solubility and can dissolve in various solvents such as water, alcohols, and ethers.

Applications:

1. Pyrrolidine finds extensive use in the field of pharmaceutical synthesis, serving as an intermediate in the synthesis of many drugs.
2. It is employed as a catalyst and ligand in organic synthesis reactions.
3. Pyrrolidine is also utilized as a solvent in chemical processes such as paint, coatings, and dye production.

Synthesis:

There are two primary methods for synthesizing pyrrolidine:

1. Mandelic reaction: Involves the reaction of pyrrolidine with hydrogen in the presence of a copper hydride catalyst.
2. Palladium-catalyzed reduction: In this method, pyrrole reacts with hydrogen in the presence of a palladium catalyst to yield pyrrolidine.

Safety Information:

1. Pyrrolidine has low toxicity, but prolonged exposure and inhalation should still be avoided.
2. When working with pyrrolidine, protective measures such as wearing safety goggles, gloves, and protective clothing should be taken, and adequate ventilation ensured.
3. Avoid contact with open flames and high temperatures to prevent explosions or fires.
4. In case of skin or eye contact, rinse immediately with plenty of water and seek medical assistance.

Other Name for Pyrrolidine：

Azolidine
Prolamine
Pyrrolidin
Pyrrolidine
Pyrrolidene
Butylenimine
perhydroazole
pyrrolidinium
Azacyclopentane
pyrrolidinering
Perhydropyrrole
tetrahydroazole
Tetrahydropyrrol
Tetramethylenimin
1-AZACYCLOPENTANE
AKOS BBS-00003603
Tetrahydropyrrole
Tetrahydro-pyrrole
Tetramethylenimine
PYRROLIDINE,REAGENT
TETRAMETHYLENEIMINE
Pyrrole, tetrahydro-
pyrrolidine,tetrahydropyrrole
TETRAHYDROPYRROLE(PYRROLIDINE)

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