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BENZOCAINE(ETHYL 4-AMINOBENZOATE)
BENZOCAINE(ETHYL 4-AMINOBENZOATE)
CAS 94-09-7
- Benzocaine is a colorless crystalline powder, odorless, with a slightly sweet taste.
- It is practically insoluble in water but can dissolve in organic solvents such as ethanol, ether, and chloroform.
- Primarily utilized as a local anesthetic, benzocaine is commonly found in oral care products, topical ointments, and sprays, used to alleviate gum pain, oral ulcers, and skin itching.
- It is also employed in certain medical and cosmetic procedures as a component of local anesthetic formulations.
Benzocaine, also known as ethyl aminobenzoate, is a local anesthetic commonly used to alleviate mild skin itching and oral discomfort. Here’s some information regarding benzocaine’s properties, uses, production, and safety:
Properties:
- Benzocaine is a colorless crystalline powder, odorless, with a slightly sweet taste.
- It is practically insoluble in water but can dissolve in organic solvents such as ethanol, ether, and chloroform.
Uses:
- Primarily utilized as a local anesthetic, benzocaine is commonly found in oral care products, topical ointments, and sprays, used to alleviate gum pain, oral ulcers, and skin itching.
- It is also employed in certain medical and cosmetic procedures as a component of local anesthetic formulations.
Production:
- Benzocaine is typically synthesized by the reaction of p-nitroaniline with acetyl chloride or ethyl acetate.
- Industrially, it can also be prepared through reactions involving compounds such as p-nitrophenol and p-aminomethyltoluene.
Safety Information:
- When used in appropriate doses and according to instructions, benzocaine is generally safe.
- Prolonged or excessive use of benzocaine may lead to adverse reactions such as allergic reactions, skin inflammation, or irritation.
- Individuals with allergies, pregnant or breastfeeding women, and children should consult a doctor before use.
- Avoid contact with eyes and oral mucosa during application.
Please note that the above information is general, and specific dosage and safety considerations should be determined based on individual circumstances and medical advice. Before using benzocaine or any other medication, be sure to read and follow the instructions and warnings in the medication’s package insert.
The overview of the chemical’s properties:
| Property | Value |
|---|---|
| CAS | 94-09-7 |
| EINECS | 202-303-5 |
| Chemical Formula | C9H11NO2 |
| Molecular Weight | 165.19 |
| Density | 1.17 |
| Melting Point | 88-90°C |
| Boiling Point | 172°C (12.7517 mmHg) |
| Flash Point | 172°C/13mm |
| Water Solubility | Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water |
| Vapor Pressure | 0.000589mmHg at 25°C |
| Solubility | Alcohol: Soluble in 5 mL per 1 gm |
| Refractive Index | 1.5600 (estimate) |
| Acidity Constant | 2.5 (at 25°C) |
| Storage Conditions | 2-8°C |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| Appearance | Crystalline powder |
| Color | White |
Other names for Benzocaine:
NSC 4688
Benzocaine
Benzocione
H-4-Abz-OEt
Benzocaine, USP, EP
Ethyl 4-aminobenzoate
Ethyl p-aminobenzoate
4-(Ethoxycarbonyl)phenylaMine
4-(ethoxycarbonyl)aniliniumato
(p-(Ethoxycarbonyl)phenylaMine
4-Aminobenzoic acid ethyl ester
Benzocaine(See B197952 for Labelled)
4-Aminobenzoic Acid Ethyl EsterBenzocaine
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