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What is Tetracaine CAS 94-24-6 and its application?

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Tetracaine, alternatively known as 2-butylamino-4-(diethylamino)benzoate, represents a local anesthetic. Here’s an overview of its properties, uses, synthesis, and safety information:

Other Names:

Anetain
Tetracaine
amethocaine
tetracaine usp
Tetracaine Base
tetracaine free base
Dimethylaminoethylnbutylaminobenzoate
2-dimethylaminoethylp-butylaminobenzoate
2-(dimethylamino)ethyl 4-(butylamino)benzoate
2-(Dimethylamino)ethyl p-(butylamino)benzoate
2-(Dimethylamino)ethyl 4-(butylamino)benzoate
2-(Dimethylamino)ethyl 4-(n-butylamino)benzoate
4-(butylamino)-benzoicaci2-(dimethylamino)ethylester
2-dimethylaminoethylesterkyselinyp-butylaminobenzoove
2-Dimethylaminoethylester kyseliny p-butylaminobenzoove

Tetracaine, alternatively known as 2-butylamino-4-(diethylamino)benzoate, represents a local anesthetic. Here’s an overview of its properties, uses, synthesis, and safety information:

Properties:

  • Appearance: Tetracaine manifests as a white crystalline solid or colorless crystalline powder.
  • Solubility: It exhibits limited solubility in water but can dissolve in alcohols, ethers, and chloroform.
  • Density: Tetracaine has a density of 1.0-1.1 g/cm³.
  • Structure: As a member of the ester class of anesthetics, Tetracaine delivers localized anesthetic effects.

Uses:

  • Pain Relief: Primarily utilized for local anesthesia, Tetracaine alleviates pain by blocking nerve conduction.
  • Medical Procedures: Tetracaine finds common usage in various surgeries, including dental, dermatological, and minor surgeries.
  • Treatment of Arrhythmias: It can be employed in managing arrhythmias by restoring normal heart rhythm through the inhibition of cardiac cell electrical signaling.

Synthesis: Tetracaine is typically synthesized by reacting 4-aminobenzoic acid with 2-(diethylamino)ethyl chloride to yield the intermediate compound, which then reacts with butylamine to produce Tetracaine.

Safety Information:

  • Due to its pharmaceutical nature, Tetracaine should be used under medical supervision to avoid overuse or prolonged usage.
  • Possible side effects may include allergic reactions, neurological issues, and cardiovascular problems. Immediate medical attention is necessary if such symptoms occur.
  • Certain individuals, such as those allergic to Tetracaine, patients with heart conditions, and pregnant women, may face specific risks.
  • Prior to using Tetracaine, it’s essential to inform the doctor about personal health conditions, history of drug allergies, and medications being taken.

In conclusion, Tetracaine serves as a valuable agent for local anesthesia, commonly applied in surgeries and pain management. However, prudent usage, avoidance of side effects, and adherence to medical guidance are imperative during its administration.


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